script for kinetic fitting of β-lactam hydrolysis using the lambert function Search Results


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Image Search Results


Compounds discontinued or likely to have been discontinued from clinical development since 2018 or the previous review [ <xref ref-type= 23 ]" width="100%" height="100%">

Journal: The Journal of Antibiotics

Article Title: Antibiotics in the clinical pipeline as of December 2022

doi: 10.1038/s41429-023-00629-8

Figure Lengend Snippet: Compounds discontinued or likely to have been discontinued from clinical development since 2018 or the previous review [ 23 ]

Article Snippet: SPR741 + β-lactam [ , ] , polymyxin (NP); membrane permeabilizer (cell wall) , IV; G-ve (Spero) – phase-I trials (NCT03022175 and NCT03376529) completed in 2017 and development was discontinued in 2020.

Techniques: Full Display Name, Inhibition, Membrane, Phospho-proteomics